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A genome-wide association and replication study of blood pressure in Ugandan early adolescents.

Swaib Abubaker LuleAlexander J MentzerBenigna NamaraAllan G MuwenziBeatrice NassangaDennison KizitoHelen AkurutLawrence LubyayiJosephine TumusiimeChristopher ZziwaFlorence AkelloDeept GurdasaniManjinder SandhuLiam SmeethAlison M ElliottEmily L Webb
Published in: Molecular genetics & genomic medicine (2019)
Variants showing suggestive associations are worthy of future investigation. Replication results suggest that variants influencing adolescent BP may overlap somewhat with those already established in previous studies, largely based on adults in Western settings.
Keyphrases
  • young adults
  • genome wide association
  • blood pressure
  • copy number
  • mental health
  • physical activity
  • current status
  • type diabetes
  • gene expression
  • metabolic syndrome
  • dna methylation
  • skeletal muscle
  • insulin resistance