Variation in the Yaa position of collagen peptides containing azaGlycine.
Samuel D MeltonDavid M ChenowethPublished in: Chemical communications (Cambridge, England) (2018)
Herein, we report the systematic investigation of amino acid variation in the Yaa position of collagen peptides containing an adjacent azaGlycine residue. We demonstrate the reliability of azaGlycine as a glycine replacement and provide a sequence independent strategy for stabilizing the triple helical assembly of collagen peptides.