Peripheral blood cellular immunophenotype in depression: a systematic review and meta-analysis.

Éimear M FoleyJoel T ParkinsonRuth E MitchellLorinda TurnerGolam M Khandaker

Published in: Molecular psychiatry (2022)

Depression is characterised by widespread alterations in circulating myeloid and lymphoid cells, consistent with dysfunction in both innate and adaptive immunity. Immune cells could be useful biomarkers for illness subtyping and patient stratification in future immunotherapy trials of depression, along with cytokines, other biomarkers, and clinical measures.

Keyphrases

peripheral blood
depressive symptoms
sleep quality
induced apoptosis
oxidative stress
case report
acute myeloid leukemia
dendritic cells
physical activity