Heredity Indexes for Estimating Heritability Using Known and Unknown Family Data Based on the Model of Polygenic Inheritance.

Published in: Computational and mathematical methods in medicine (2020)

Our findings indicate the reliability of the model based on the fact that the multigene effect constitutes the normal distribution. Thus, this model can be used for comprehensive analysis of the influence of genetic and nongenetic factors on the genetic phenotype and to estimate genetic risk using known and unknown family data.

Keyphrases

genome wide
copy number
electronic health record
mitochondrial dna
gene expression
machine learning
dna methylation