Serial FLT PET imaging to discriminate between true progression and pseudoprogression in patients with newly diagnosed glioblastoma: a long-term follow-up study.
Cyrillo G BrahmMartha W den HollanderRoelien H EntingJan Cees de GrootA Millad SoloukiWilfred F A den DunnenMart A A M HeestersMichiel WagemakersHenk M W VerheulElisabeth G E de VriesJan PruimAnnemiek M E WalenkampPublished in: European journal of nuclear medicine and molecular imaging (2018)
Baseline FLT uptake appears to be predictive of overall survival. Furthermore, changes in SUVmax over time showed a tendency to be associated with improved survival. However, further studies are necessary to investigate the ability of FLT PET imaging to discriminate between true progression and pseudoprogression in patients with glioblastoma.