Investigating plasma volume expanders as novel macromolecular MRI-CEST contrast agents for tumor contrast-enhanced imaging.
Lorena ConsolinoPietro IrreraFeriel RomdhaneAnnasofia AnemoneDario Livio LongoPublished in: Magnetic resonance in medicine (2021)
The obtained results showed that both voluven and dextran 70 can be exploited as MRI-CEST contrast agents for evaluating tumor enhancement properties. Their increased accumulation in tumors and prolonged contrast enhancement promote their use as blood-pool MRI-CEST agents to examine tumor vascularization.