Global burden of disease: acute-on-chronic liver failure, a systematic review and meta-analysis.

Gabriel MezzanoAdria JuanolaAndres CardenasEsteban MezeyJames P HamiltonElisa PoseIsabel GrauperaPere GinèsElsa SolàFasiha Kanwal

Published in: Gut (2021)

The global prevalence and mortality of ACLF are high. Region-specific variations could be explained by the type of triggers/aetiology of CLD or grade. Health systems will need to tailor early recognition and treatment of ACLF based on region-specific data.

Keyphrases

liver failure
hepatitis b virus
risk factors
cardiovascular events
type diabetes
drug induced
coronary artery disease
respiratory failure
intensive care unit
combination therapy
deep learning
data analysis
mechanical ventilation
aortic dissection