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New insights into genetic variant spectrum and genotype-phenotype correlations of Rubinstein-Taybi syndrome in 39 CREBBP-positive patients.

Virginia Pérez-GrijalbaAlberto García-OguizaMaría LópezJudith ArmstrongSixto García-MiñaurJose María Mesa-LatorreMar O'CallaghanMercé Pineda MarfaMaria Antonia Ramos-ArroyoFernando Santos-SimarroVerónica SeidelElena Dominguez Garrido
Published in: Molecular genetics & genomic medicine (2019)
Seventeen of the 40 genetic variants detected were reported for the first time in this work contributing, thus, to expand the molecular knowledge of this complex disorder.
Keyphrases
  • end stage renal disease
  • ejection fraction
  • newly diagnosed
  • healthcare
  • chronic kidney disease
  • prognostic factors
  • genome wide
  • single molecule