Efficacy and safety of pharmacological cachexia interventions: systematic review and network meta-analysis.

Manit SaeteawPhitjira SanguanboonyaphongJukapun YoodeeKaitlyn CraftRatree SawangjitNuttapong NgamphaiboonPrapimporn Chattranukulchai ShantavasinkulSuphat SubongkotNathorn Chaiyakunapruk

Published in: BMJ supportive & palliative care (2020)

Our findings suggest that several pharmacological interventions have potential to offer benefits in treatment of cachexia especially Megace_H and short-term use corticosteroids. Nonetheless, high-quality comparative studies to compare safety and efficacy are warranted for better management of cachexia.

Keyphrases

physical activity
case control
combination therapy
risk assessment
human health
replacement therapy