Effect of Prior Embolization on Outcomes After Stereotactic Radiosurgery for Pediatric Brain Arteriovenous Malformations: An International Multicenter Study.
Rebecca M BurkeChing-Jen ChenDale DingThomas J BuellJennifer SokolowskiKimball A SheehanCheng-Chia LeeDarrah E SheehanHideyuki KanoKathryn N KearnsShih-Wei TzengHuai-Che YangPaul P HuangDouglas KondziolkaNatasha IronsideDavid MathieuChristian Iorio-MorinInga S GrillsCaleb FelicianoGene BarnettRobert M StarkeL Dade LunsfordJason P SheehanPublished in: Neurosurgery (2021)
Embolization appears to decrease cumulative obliteration rates after SRS for pediatric AVMs without affecting the risk of post-treatment hemorrhage or adverse radiation effects arguing against the routine use of pre-SRS embolization. While endovascular therapy can be considered for occlusion of high-risk angioarchitectural features prior to SRS, future studies are necessary to clarify its role.