Photobiomodulation therapy's effects on cardiac fibrosis activation after experimental myocardial infarction.
Regiane Dos S FelicianoMartha T ManchiniAllan L B AtumGabriel Almeida da SilvaEdnei L AntônioAndrey Jorge SerraPaulo J F TucciRamon Andrade de MelloMaria C ChavantesOvidiu Constantin BaltatuJosé Antônio Silva JúniorPublished in: Lasers in surgery and medicine (2022)
The results suggest that PBMT, through the modulation of gene transcription and miRNA expressions, can interfere in cardiac fibrosis activation after MI, mainly reversing the signaling pathway of profibrotic genes.