Recurrence of immune complex and complement-mediated membranoproliferative glomerulonephritis in kidney transplantation.
Fernando Caravaca-FontánNatalia PolancoBlanca VillacortaAnna BuxedaArmando Coca-RojoAna ÁvilaRocío Martínez-GallardoCristina GaleanoRosalía ValeroNatalia RamosNatalia AllendeLeónidas Cruzado-VegaMaría José Pérez-SáezÁngel SevillanoEsther GonzálezAna HernándezEmilio RodrigoMario Fernández-RuizJosé María AguadoMiguel Ángel Pérez ValdiviaJulio PascuallAmado AndrésManuel PragaPublished in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association (2022)
One-fourth of patients with native kidney disease due to MPGN developed clinical recurrence in the allograft, especially in cases with complement-mediated disease or in those associated with dysproteinemia. The kidney outcomes of disease recurrence with currently available therapies are heterogeneous and thus, more effective and individualized therapies are needed.