Bleeding events in people with congenital haemophilia A without factor VIII inhibitors receiving prophylactic factor VIII treatment: A systematic literature review.
Pier Mannuccio MannucciCraig M KesslerFederico GerminiFrancis NissenRichard Ofori-AsensoCristian BrocchieriSara BendinelliAlfonso IorioPublished in: Haemophilia : the official journal of the World Federation of Hemophilia (2023)
This meta-analysis shows that PwcHA without inhibitors still have bleeds despite FVIII prophylaxis. Improved standardization on capturing and reporting bleeding outcomes is needed so that effective comparisons between treatments can be made.