Trigger of apoptosis in adenocarcinoma gastric cell line (AGS) by a complex of thiosemicarbazone and copper nanoparticles.

Mahsa Badrooh Faezeh Shokrollahi Shaghayegh Javan Taraneh Ghasemipour Samira Rezaei Mojdehi Haniyeh Farahnak Mahboubeh Jahani Sayyad Noveiri Mohammad Hedayati Ali Salehzadeh

Published in: Molecular biology reports (2022)

This study introduced CuO@Glu/TSC as an efficient anticancer against gastric cancer cells with lower toxicity toward normal cells which could be employed for cancer treatment after further studies.

Keyphrases

cell cycle arrest
induced apoptosis
oxidative stress
endoplasmic reticulum stress
cell death
squamous cell carcinoma
pi k akt
oxide nanoparticles