GLIPR1L1 is an IZUMO-binding protein required for optimal fertilization in the mouse.

Avinash S GaikwadAmanda L AndersonD Jo MerrinerAnne E O'ConnorBrendan J HoustonR John AitkenMoira K O'BryanBrett Nixon

Published in: BMC biology (2019)

Collectively, this study characterizes multimeric protein complexes on the sperm surface and identifies GLIPRL1L1 as a physiologically relevant regulator of IZUMO1 function and the fertilization process.

Keyphrases

binding protein
genome wide
transcription factor
dna methylation
protein protein