Class Ⅱ malocclusion is one of the factors inducing poor appearance and occlusal dysfunction in adolescents, which affects their physical and mental development. The success of treatment in correction class Ⅱ malocclusion in adolescents is dependent on the appropriate choice of therapy timing and methods, because of multifaceted causes. And puberty represents an essential period for development improvement. In the meantime, precise risk prevention and management are also conducive to the enhance treatment outcomes. A comprehension of the diagnosis, therapy, and risk control of adolescents class Ⅱ malocclusion will be discussed.