Characteristics and time course of acute and chronic myocardial lesion formation after electroporation ablation in the porcine model.
Kars NevenVincent J H M van DrielAryan VinkBastiaan C du PréHarry van WesselAnna FütingPieter A DoevendansFred H M WittkampfRené van EsPublished in: Journal of cardiovascular electrophysiology (2022)
Electroporation ablation immediately induces contraction band necrosis and edema without additional tissue changes in the first hour. After 3 weeks, a sharply demarked scar has been developed that remains stable during follow-up of 3 months. This is highly relevant for clinical application of electroporation ablation in terms of the electrophysiological endpoint and waiting period after ablation.