Extracorporeal therapy of sepsis by purified granulocyte concentrates - ex vivo circulation model.
Gerd KlinkmannThomas WildBenjamin HeskampFanny DossSandra DossMagdalena MilejLea-Marie ThieleLilia GoudevaRainer BlasczykDaniel A ReuterJens AltrichterSteffen MitznerPublished in: Artificial organs (2023)
The granulocytes demonstrated full functionality in the 6 hours extracorporeal circuits after 3 days storage and in septic shock plasma. This is demonstrating the functionality of the system and encourages further clinical studies.