Effects of Carbidopa Premedication on 18F-FDOPA PET Imaging of Glioma: A Multiparametric Analysis.

Marie BrosTimothée ZaragoriFabien RechMarie BlonskiGabriela HossuLuc TaillandierPierre-Yves MarieAntoine Verger

Published in: Cancers (2021)

In 18F-FDOPA PET, carbidopa induces similarly higher SUV and TTP dynamic parameters and similarly impacts SUV-dependent radiomics in healthy brain and tumor regions, which is compensated for by correcting for the tumor-to-healthy-brain ratio. This is a significant advantage for multicentric study harmonization.

Keyphrases

pet imaging
resting state
white matter
positron emission tomography
functional connectivity
computed tomography
squamous cell carcinoma
contrast enhanced