A RAB transition orchestrates membrane trafficking in unconventional protein secretion.

Yuxin SunMin ZhangLiang Ge

Published in: The Journal of cell biology (2024)

Rab GTPases function as intracellular molecular switches that regulate vesicular transport. In the current issue, Li et al. (https://doi.org/10.1083/jcb.202306107) revealed RAB-8 to RAB-11 transition governing the unconventional secretion of membrane proteins in the intestinal epithelium of C. elegans.

Keyphrases

single cell
amino acid
protein protein
small molecule