Lysophosphatidylcholine facilitates the pathogenesis of psoriasis through activating keratinocytes and T cells differentiation via glycolysis.

Panpan LiuYouyou ZhouChao ChenBei YanLei LiWu Zhu Runqiu LiuMingLiang ChenJuan Su Yehong Kuang Xiang Chen Cong Peng

Published in: Journal of the European Academy of Dermatology and Venereology : JEADV (2023)

Taken together, our findings revealed the role of the LPC/G2A axis in the pathogenesis of psoriasis; targeting LPC/G2A is a potential strategy for psoriasis therapy.

Keyphrases

atopic dermatitis
single cell
signaling pathway
bone marrow
climate change
mesenchymal stem cells
cell therapy