Somatotropic Axis Dysfunction in Non-Alcoholic Fatty Liver Disease: Beneficial Hepatic and Systemic Effects of Hormone Supplementation.

Daniel CabreraClaudio Cabello-VerrugioNancy SolísDiego San MartínCatalina CofréMargarita PizarroJuan Pablo ArabJohanna AbrigoFabián CamposBetzabé IrigoyenGonzalo Carrasco-AvinoKatiuska BezaresValentina RiquelmeArnoldo RiquelmeMarco ArreseFrancisco Barrera

Published in: International journal of molecular sciences (2018)

GH and IGF-1 supplementation induced significant improvement in liver steatosis, aminotransferases and sarcopenia in a diet-induced NAFLD model.

Keyphrases

growth hormone
diabetic rats
high glucose
insulin resistance

oxidative stress
drug induced
high fat diet

pi k akt
high fat diet induced
liver fibrosis

signaling pathway
cell proliferation
stress induced