Molecular subtypes based on DNA methylation predict prognosis in lung squamous cell carcinoma.

Xiu-Shen LiKe-Chao NieZhi-Hua ZhengRui-Sheng ZhouYu-Sheng HuangZeng-Jie YeFan HeYing Tang

Published in: BMC cancer (2021)

Models based on differences in DNA methylation levels may help to classify the molecular subtypes of LUSC patients, and provide more individualized treatment recommendations and prognostic assessments for different clinical subtypes. GNAS, FZD2, FZD10 are the core three genes that may be related to the prognosis of LUSC patients.

Keyphrases

dna methylation
end stage renal disease
squamous cell carcinoma
ejection fraction
chronic kidney disease
newly diagnosed
genome wide
gene expression
peritoneal dialysis
prognostic factors
radiation therapy
patient reported outcomes
transcription factor
single molecule
genome wide analysis