Infants with cystic fibrosis have altered fecal functional capacities with potential clinical and metabolic consequences.

Alexander EngHillary S HaydenChristopher E PopeMitchell J BrittnacherAnh T VoEli J WeissKyle R HagerDaniel H LeungSonya L HeltsheDaniel RafterySamuel I MillerLucas R HoffmanElhanan Borenstein

Published in: BMC microbiology (2021)

Our results highlight several metagenomic and metabolomic factors, including bile acids and other microbial metabolites, that may impact nutrition, growth, and GI health in infants with CF. These factors could serve as promising avenues for novel microbiome-based therapeutics to improve health outcomes in these infants.

Keyphrases

healthcare
public health
cystic fibrosis
physical activity
mental health
microbial community
ms ms
small molecule
human health
risk assessment
wastewater treatment
health promotion