Education modulates brain maintenance in presymptomatic frontotemporal dementia.
Stefano GazzinaMario GrassiEnrico PremiMaura CossedduAntonella AlbericiSilvana ArchettiRoberto GasparottiJohn Cornelis van SwietenDaniela GalimbertiRaquel Sanchez-ValleRobert Jr LaforceFermin MorenoMatthis SynofzikCaroline GraffMario MasellisMaria Carmela TartagliaJames Benedict RoweRik VandenbergheElizabeth C FingerFabrizio TagliaviniAlexandre de MendonçaIsabel SantanaChristopher R ButlerSimon DucharmeAlex GerhardAdrian DanekJohannes LevinMarkus OttoGiovanni FrisoniSandro SorbiAlessandro PadovaniJonathan D RohrerBarbara Borroninull nullPublished in: Journal of neurology, neurosurgery, and psychiatry (2019)
This longitudinal study demonstrates that even in presence of ongoing pathological processes, education may facilitate both brain reserve and brain maintenance in the presymptomatic phase of genetic FTD.