Cerebrospinal fluid proteins in idiopathic intracranial hypertension: An exploratory SWATH proteomics analysis.

Awadh Kishor Pandit Shubham MisraShantanu SenguptaRahul ChakrabortyPraveen SinghGyaninder Pal SinghSwati PhuljheleAchal K SrivastavaDeepti VibhaAjay GargVivek ShankarDheeraj MohaniaGarima ShuklaKameshwar Prasad

Published in: Proteomics. Clinical applications (2023)

Neurosecretory, neuroendocrine, and inflammatory proteins were predominantly involved in causing IIH. This exploratory study served as a platform to identify 37 differentially expressed proteins in IIH and also showed significant differences between overweight and non-overweight IIH patients.

Keyphrases

cerebrospinal fluid
end stage renal disease
weight loss
blood pressure
ejection fraction
chronic kidney disease
newly diagnosed
physical activity
weight gain
mass spectrometry
prognostic factors
high throughput