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Molecular characteristics of low-grade serous carcinoma in effusions.

Delfim DoutelBen DavidsonIna Katrine Nitschke PettersenAnnette Torgunrud
Published in: Cytopathology : official journal of the British Society for Clinical Cytology (2023)
The molecular alterations in LGSCs in serous effusions are consistent with the ones found in solid tumors, with frequent alterations in the MAPK pathway. Mutations in LGSC may be a marker of better outcome.
Keyphrases
  • high grade
  • low grade
  • signaling pathway
  • oxidative stress
  • pi k akt
  • cell proliferation