Cilia loss on distinct neuron populations differentially alters cocaine-induced locomotion and reward.
Thomas EverettTyler W Ten EyckChang-Hung WuAmanda L ShelowitzSofia M StansburyAlexandra FirekBarry SetlowJeremy C McIntyrePublished in: Journal of psychopharmacology (Oxford, England) (2023)
Combined with previous findings using amphetamine, our results show that behavioral effects of cilia ablation are cell- and drug type-specific, and that neuronal cilia contribute to modulation of both the locomotor-inducing and rewarding properties of cocaine.