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Chemotherapy Coupled to Macrophage Inhibition Induces T-cell and B-cell Infiltration and Durable Regression in Triple-Negative Breast Cancer.

Swarnima SinghNigel LeeDiego A PedrozaIgor L BadoClark HamorLicheng ZhangSergio AguirreJingyuan HuYichao ShenYitian XuYang GaoNa ZhaoShu-Hsia ChenYing-Wooi WanZhandong LiuJeffrey T ChangDaniel HollernCharles M PerouXiang H F ZhangJeffrey M Rosen
Published in: Cancer research (2022)
Immunostimulatory chemotherapy combined with pharmacologic inhibition of TAMs results in durable treatment responses elicited by Th cells and B cells in claudin-low TNBC models.
Keyphrases
  • induced apoptosis
  • locally advanced
  • cell cycle arrest
  • adipose tissue
  • squamous cell carcinoma
  • rectal cancer
  • oxidative stress
  • cell proliferation