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Clinical and electrocardiographic factors associated with adverse cardiovascular events in bupropion exposures.

Michael D SimpsonAndrew TrogerChris FengJames D WhitledgeMichael MonuteauxMichele M Burns
Published in: Clinical toxicology (Philadelphia, Pa.) (2023)
Increasing age, seizures, QRS widening, and QTc prolongation were associated with adverse cardiovascular events in bupropion exposures. Adverse cardiovascular events did not occur in unintentional exposures. Further research is needed to develop screening tools and treatments for bupropion cardiotoxicity.
Keyphrases
  • cardiovascular events
  • coronary artery disease
  • air pollution
  • cardiovascular disease
  • adverse drug
  • left ventricular
  • type diabetes
  • chemotherapy induced