Closed-Loop Therapy and Preservation of C-Peptide Secretion in Type 1 Diabetes.
Charlotte K BoughtonJanet M AllenJulia WareMalgorzata E WilinskaSara HartnellAjay ThankamonyTabitha RandellAtrayee GhatakRachel Elizabeth Jane BesserDaniela ElleriNicola TrevelyanFiona M CampbellJudy SibayanPeter CalhounRyan BaileyGareth DunseathRoman Hovorkanull nullPublished in: The New England journal of medicine (2022)
In youths with new-onset type 1 diabetes, intensive glucose control for 24 months did not appear to prevent the decline in residual C-peptide secretion. (Funded by the National Institute for Health and Care Research and others; CLOuD ClinicalTrials.gov number, NCT02871089.).