Analysis of Epigenetic Alterations in Homologous Recombination DNA Repair Genes in Male Breast Cancer.

Saudade AndréSandra P NunesFernanda SilvaRui M Henrique Ana Felix Carmen Jerónimo

Published in: International journal of molecular sciences (2020)

Quantitative promoter methylation of RAD51B and XRCC3 constitutes a promising and accurate biomarker for male BC. Validation in larger series and in liquid biopsies is warranted to confirm its usefulness in detection and monitoring settings.

Keyphrases

dna repair
dna methylation
dna damage
genome wide
gene expression
dna damage response
high resolution
transcription factor
oxidative stress
real time pcr
mass spectrometry
young adults
quantum dots