Stem cells from human exfoliated deciduous teeth correct the immune imbalance of allergic rhinitis via Treg cells in vivo and in vitro.

Yu-Yang DaiSi-Yang NiKe MaYu-Shi MaZhi-Shi WangXiu-Li Zhao

Published in: Stem cell research & therapy (2019)

These results suggest that SHEDs could correct the CD4+ T cell immune imbalance via Treg cells and may be potential therapeutic agents for the treatment of allergic diseases, such as AR, in the future.

Keyphrases

allergic rhinitis
induced apoptosis
stem cells
cell cycle arrest
endoplasmic reticulum stress
cell death
oxidative stress
signaling pathway
atopic dermatitis