Alpha radionuclide-chelated radioimmunotherapy promoters enable local radiotherapy/chemodynamic therapy to discourage cancer progression.
Jiajia ZhangFeize LiYuzhen YinNing LiuMengqin ZhuHan ZhangWeihao LiuMengdie YangShanshan QinXin FanYuanyou YangKun ZhangFei YuPublished in: Biomaterials research (2022)
The tri-model TAT-CDT-ICB strategy provides a long-term immunological memory, which can protect against tumor rechallenge after eliminating original tumors. Therefore, this work presents a novel approach for TAT-CDT-ICB tri-modal cancer therapy with repressed metastasis and relapse in clinics.