Profiling Bacteria in the Lungs of Patients with Severe Influenza Versus COVID-19 with or without Aspergillosis.
Simon FeysMartina Cardinali-BenigniHanne Moon LauwersCato JacobsAnnelies StevaertSamuel M GonçalvesCristina CunhaYves DebaveyeGreet HermansJannes HeylenStephanie Humblet-BaronKatrien LagrouLenn MaessenPhilippe MeerssemanMarijke PeetermansAlvaro Redondo-RiosLaura SeldeslachtsMarick R StarickKarin ThevissenGreetje Vande VeldeChristophe VandenbrieleLore VanderbekeAlexander WilmerLieve NaesensFrank L van de VeerdonkJohan Van WeyenberghToni GabaldónJoost WautersAgostinho CarvalhoPublished in: American journal of respiratory and critical care medicine (2024)
Aspergillosis is more frequently detected in lungs of severe influenza patients than bacterial pathogens. Detection of bacterial pathogens associates with worse outcome in influenza patients, particularly in those with IAPA, but not in COVID-19 patients. The immunological dynamics of tripartite viral-fungal-bacterial interactions deserve further investigation. This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives License 4.0 (http://creativecommons.org/licenses/by-nc-nd/4.0/).