Oncostatin M promotes epithelial barrier dysfunction in patients with eosinophilic chronic rhinosinusitis with nasal polyps.

Bao-Feng WangYing-Ying WangHai LinYun-Lan Yi

Published in: Tissue barriers (2024)

OSM induces the synthesis and release of MMP-1 and -7 in NECs. Furthermore, MMP-1 and -7 promote mucosal epithelial barrier dysfunction in patients with Eos CRSwNP.

Keyphrases

chronic rhinosinusitis
oxidative stress
cell migration
ulcerative colitis