Computational Fluid Dynamics (CFD) Guided Spray Drying Recommendations for Improved Aerosol Performance of a Small-Particle Antibiotic Formulation.

Philip Worth LongestAmr HassanDale FarkasMichael Hindle

Published in: Pharmaceutical research (2022)

Based on the newly recommended spray dryer conditions for small particle aerosols, delivery performance of the lead Tobi-EEG formulation was improved resulting in >60% of the DPI loaded dose passing through the pediatric MT model.

Keyphrases

drug delivery
water soluble
cancer therapy
working memory
functional connectivity
clinical practice
wound healing