Increased number of monocytes and plasma levels of MCP-1 and YKL-40 in first-episode psychosis.

F OrhanL SchwielerH Fatouros-BergmanA MalmqvistS CervenkaK CollsteL FlycktL FardeC M SellgrenF Piehlnull nullGöran EngbergS Erhardt

Published in: Acta psychiatrica Scandinavica (2018)

These data demonstrate activation of monocytes in FEP and strengthens the idea of an immune dysfunction of psychotic disorders. Further studies are required to perceive a role of YKL-40 and MCP-1 in the initiation and progression of schizophrenia.

Keyphrases

bipolar disorder
dendritic cells
peripheral blood
electronic health record
oxidative stress
big data
immune response
data analysis
artificial intelligence