Downregulation of miR-137 Facilitates CD4+ T Cell Pyroptosis in Systemic Lupus Erythematosus via Stimulating AMPK Pathway.
Aimin GongLong MiFangzhi WeiYanping ZhuangYitian SongChengdan PanXuan ZhangGuiling LinZhiquan WuYing LiuPublished in: Journal of immunology research (2023)
Upregulating miR-137 inhibits CD4+ T cell pyroptosis in SLE patients by modulating the AMPK pathway, suggesting the potential diagnostic and therapeutic role of miR-137 in SLE.
Keyphrases
- cell proliferation
- long non coding rna
- systemic lupus erythematosus
- long noncoding rna
- end stage renal disease
- chronic kidney disease
- ejection fraction
- newly diagnosed
- skeletal muscle
- disease activity
- signaling pathway
- nlrp inflammasome
- prognostic factors
- peritoneal dialysis
- rheumatoid arthritis
- risk assessment
- patient reported outcomes
- patient reported