Tumor-secreted IFI35 promotes proliferation and cytotoxic activity of CD8 + T cells through PI3K/AKT/mTOR signaling pathway in colorectal cancer.

Peisi LiDawang ZhouDongwen ChenYikan ChengYuan ChenZhensen LinXi ZhangZhihong HuangJiawei CaiWenfeng HuangYanyun LinHaoxian KeJiahui LongYifeng ZouShubiao YePing Lan

Published in: Journal of biomedical science (2023)

T cells, as well as increase the efficacy of CAR-T cells against colorectal cancer cells.

Keyphrases

signaling pathway
pi k akt
induced apoptosis
epithelial mesenchymal transition
oxidative stress
endoplasmic reticulum stress