Raynaud's Phenomenon of the Nipple: Epidemiological, Clinical, Pathophysiological, and Therapeutic Characterization.
Thaís Gomes MoreiraGiovana Mamede CastroJucier Gonçalves JúniorPublished in: International journal of environmental research and public health (2024)
Raynaud's phenomenon of the nipple is a possible cause of pain and breastfeeding cessation in lactating women. However, there are still few studies on the characterization of this manifestation. Thus, we aim to develop a systematic review of the literature carried out between January 1992 and January 2024 in PubMed, Scopus, Web of Science, Virtual Health Library (VHL), and Portal de Periódicos da CAPES. Of the 438 articles, 19 met the eligibility criteria. The findings were divided by heuristic questions into two groups: "Epidemiological, pathophysiological, and clinical characterization of Raynaud's Phenomenon of the nipple" and "Treatment of Raynaud's Phenomenon of the nipple". Raynaud's phenomenon of the nipple is commonly primary, being more prevalent in the postpartum period, in women with a mean age of 32 years. The main triggers appear to be stress and temperature change. Generally, it is associated with a change in color and pain during breastfeeding. A calcium channel blocker was the most used medication with or without non-pharmacological measures.
Keyphrases
- breast reconstruction
- chronic pain
- public health
- healthcare
- preterm infants
- pain management
- neuropathic pain
- polycystic ovary syndrome
- mental health
- pregnant women
- heat stress
- metabolic syndrome
- risk assessment
- spinal cord
- emergency department
- tyrosine kinase
- climate change
- health information
- angiotensin converting enzyme
- stress induced
- angiotensin ii
- pregnancy outcomes
- insulin resistance
- social media