Population pharmacokinetics of cisplatin in small cell lung cancer patients guided with informative priors.
Jurij Aguiar ZdovcMihaela VaupotičGregor MaroltLea KnezRenata Režonja KukecTanja ČuferTomaž VovkIztok GrabnarPublished in: Cancer chemotherapy and pharmacology (2022)
We developed a tool to individualize cisplatin dosing based on the estimated probability of neutropenia. The benefit of more intense dosing regimens in SCLC patients should be further assessed.