Toxigenic Clostridium perfringens Isolated from At-Risk Paediatric Inflammatory Bowel Disease Patients.
James KuoJasmina UzunovicAmanda JacobsonMichelle DouradoSarah GierkeManohary RajendramDaniela KeilbergJordan MarEmily StekolJoanna CurrySofia VerstraeteJessica LundYuxin LiangFiona B TamburiniNatalie S OmattageMatthieu MasureelSteven T RutherfordDavid H HackosMan-Wah TanAllyson L ByrdMary E KeirElizabeth SkippingtonKelly M StorekPublished in: Journal of Crohn's & colitis (2024)
Gastrointestinal carriage of certain toxigenic C. perfringens may have an important pathogenic impact on IBD patients. These findings support routine monitoring of C. perfringens and PFO toxins and potential treatment in patients.