Oral health-related quality of life in Loeys-Dietz syndrome, a rare connective tissue disorder: an observational cohort study.

The dental hypersensitivity, TMJ abnormalities, self-reported poor-to-fair oral health status and cumulation of four-or-more oral manifestations had significant influence on worse OHRQoL. Specific dental treatment guidelines are necessary to ensure optimal quality of life in patients diagnosed with LDS.