Association of ACE2 variant rs4646188 with the risks of atrial fibrillation and cardioembolic stroke in Uygur patients with type 2 diabetes.
Cheng LiuJingxian PeiYanxian LaiTianwang GuanAbudurexiti ZeyaweidingTutiguli MaimaitiHaiyan ZhaoYan ShenPublished in: BMC cardiovascular disorders (2021)
These results indicated ACE2 rs4646188 was associated with increased risk of AF and CS among diabetic patients in Uygurs, which could be a promising genetic predisposition marker for early and personalized prevention strategies for the aforementioned clinical pathologies.
Keyphrases
- atrial fibrillation
- angiotensin converting enzyme
- angiotensin ii
- oral anticoagulants
- left atrial
- catheter ablation
- left atrial appendage
- direct oral anticoagulants
- heart failure
- percutaneous coronary intervention
- genome wide
- human health
- dna methylation
- gene expression
- risk assessment
- climate change
- venous thromboembolism
- acute coronary syndrome
- blood brain barrier