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Toward the "Perfect" Shunt: Historical Vignette, Current Efforts, and Future Directions.

Anthony PodgoršakFabian FlürenbrockNina Eva TrimmelLeonie KornMarkus Florian OertelLennart StieglitzSandra Fernandes DiasMelanie Michaela HierwegerMelanie ZeilingerMiriam WeisskopfMarianne Schmid Daners
Published in: Advances and technical standards in neurosurgery (2024)
As a concept, drainage of excess fluid volume in the cranium has been around for more than 1000 years. Starting with the original decompression-trepanation of Abulcasis to modern programmable shunt systems, to other nonshunt-based treatments such as endoscopic third ventriculostomy and choroid plexus cauterization, we have come far as a field. However, there are still fundamental limitations that shunts have yet to overcome: namely posture-induced over- and underdrainage, the continual need for valve opening pressure especially in pediatric cases, and the failure to reinstall physiologic intracranial pressure dynamics. However, there are groups worldwide, in the clinic, in industry, and in academia, that are trying to ameliorate the current state of the technology within hydrocephalus treatment. This chapter aims to provide a historical overview of hydrocephalus, current challenges in shunt design, what members of the community have done and continue to do to address these challenges, and finally, a definition of the "perfect" shunt is provided and how the authors are working toward it.
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