Patterns of Treatment Failure in Primary Central Nervous System Lymphoma.

James R Janopaul-NaylorJimmy S PatelManali RupjiDavid C QianKimberly B HoangNeal S McCallAshley J SchlafsteinMadison L ShoafShawn KothariJeffrey J OlsonHui-Kuo ShuJim ZhongStewart G NeillBree Eaton

Published in: American journal of clinical oncology (2024)

Our findings reaffirm the importance of systemic and intrathecal therapies for local control in PCNSL. However, bulky tumors trend to fail locally, warranting further investigation about the role of local therapies or systemic therapy intensification.

Keyphrases

diffuse large b cell lymphoma
cerebrospinal fluid
combination therapy
replacement therapy
cell therapy