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Serum matrix metalloproteinase 3 levels are associated with an effect of iguratimod as add-on therapy to biological DMARDs in patients with rheumatoid arthritis.

Nao TokaiShuzo YoshidaTakuya KotaniAyaka YoshikawaYuko KimuraYouhei FujikiYoko MatsumuraTohru TakeuchiShigeki MakinoShigeki Arawaka
Published in: PloS one (2018)
Our findings suggest that the ratios of the serum MMP-3 levels at baseline to those at 12 weeks could be used to predict remission in RA patients who are administered iguratimod as an add-on to bDMARDs.
Keyphrases
  • end stage renal disease
  • ejection fraction
  • newly diagnosed
  • rheumatoid arthritis
  • disease activity
  • peritoneal dialysis
  • prognostic factors
  • stem cells
  • systemic sclerosis
  • interstitial lung disease