Depression promotes breast cancer progression by regulating amino acid neurotransmitter metabolism and gut microbial disturbance.

Sisi LinZhe ZhouYiming QiJiabing ChenGuoshu XuYunfu ShiZhihong YuMingqian LiKequn Chai

Published in: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico (2024)

Depression promoted the progression of BC by modulating the abundance of s_Lachnospiraceae and s_Bacteroides_caecimuris, which affected the metabolism of monoamine neurotransmitters in the brain and AA in the blood.

Keyphrases

amino acid
depressive symptoms
sleep quality
microbial community
white matter
signaling pathway
resting state
young adults
brain injury
anaerobic digestion