Higher polygenic risk for melanoma is associated with improved survival in a high ultraviolet radiation setting.

Mathias Seviiri Richard A Scolyer D Timothy Timothy Bishop Julia A Newton-Bishop Mark M Iles Serigne N LôJohnathan R StretchRobyn P M SawOmgo E NiewegKerwin F ShannonAndrew J SpillaneScott D Gordon Catherine M Olsen David C Whiteman Maria Teresa Landi John F Thompson Georgina V Long Stuart Macgregor Matthew H Law

Published in: Journal of translational medicine (2022)

We found two loci potentially associated with MSS. Increased genetic susceptibility to develop CM is associated with improved MSS in a high UV setting.

Keyphrases

genome wide
gene expression
radiation therapy
radiation induced
breast cancer risk